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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAD1
All Species:
35.76
Human Site:
S578
Identified Species:
60.51
UniProt:
Q99259
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99259
NP_000808.2
594
66897
S578
S
N
P
A
A
T
Q
S
D
I
D
F
L
I
E
Chimpanzee
Pan troglodytes
Q5IS68
594
66879
S578
S
N
P
A
A
T
Q
S
D
I
D
F
L
I
E
Rhesus Macaque
Macaca mulatta
XP_001082995
594
66721
S578
S
N
P
A
A
T
Q
S
D
I
D
F
L
I
E
Dog
Lupus familis
XP_541080
543
61384
A527
S
N
P
A
T
R
R
A
D
V
D
Y
L
I
D
Cat
Felis silvestris
Mouse
Mus musculus
P48318
593
66630
S577
S
N
P
A
A
T
Q
S
D
I
D
F
L
I
E
Rat
Rattus norvegicus
P18088
593
66622
S577
S
N
P
A
A
T
Q
S
D
I
D
F
L
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514987
594
67148
S578
S
N
P
A
A
T
K
S
D
I
D
F
L
I
E
Chicken
Gallus gallus
NP_990244
590
66692
S574
S
N
P
A
A
T
K
S
D
I
D
F
L
I
E
Frog
Xenopus laevis
NP_001079270
563
64077
S547
S
N
P
A
A
T
K
S
D
I
D
F
L
V
E
Zebra Danio
Brachydanio rerio
NP_919400
587
66137
S571
S
N
H
A
V
T
K
S
D
I
D
F
L
I
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20228
510
57801
I503
V
D
F
M
L
D
E
I
H
R
L
G
D
D
L
Honey Bee
Apis mellifera
XP_391979
509
57849
M502
V
D
F
L
L
A
E
M
D
R
L
G
H
D
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784856
614
68930
A594
N
N
T
A
S
T
K
A
D
I
D
F
M
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M0G4
545
60786
K538
I
I
Q
K
H
A
S
K
F
T
R
N
D
H
Y
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
97.9
59.7
N.A.
97.1
97.1
N.A.
92.4
92.4
69.1
83.1
N.A.
50.6
49.8
N.A.
55
Protein Similarity:
100
100
98.4
75.5
N.A.
98.8
98.8
N.A.
96.1
96.4
77.9
91.4
N.A.
64.8
66.8
N.A.
71.3
P-Site Identity:
100
100
100
53.3
N.A.
100
100
N.A.
93.3
93.3
86.6
73.3
N.A.
0
6.6
N.A.
46.6
P-Site Similarity:
100
100
100
86.6
N.A.
100
100
N.A.
100
100
100
86.6
N.A.
13.3
20
N.A.
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
22.7
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
38.7
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
79
58
15
0
15
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
0
0
0
8
0
0
86
0
79
0
15
15
22
% D
% Glu:
0
0
0
0
0
0
15
0
0
0
0
0
0
0
58
% E
% Phe:
0
0
15
0
0
0
0
0
8
0
0
72
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% G
% His:
0
0
8
0
8
0
0
0
8
0
0
0
8
8
0
% H
% Ile:
8
8
0
0
0
0
0
8
0
72
0
0
0
65
0
% I
% Lys:
0
0
0
8
0
0
36
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
15
0
0
0
0
0
15
0
72
8
15
% L
% Met:
0
0
0
8
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
8
79
0
0
0
0
0
0
0
0
0
8
0
0
0
% N
% Pro:
0
0
65
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
0
0
36
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
8
0
0
15
8
0
0
0
0
% R
% Ser:
72
0
0
0
8
0
8
65
0
0
0
0
0
0
0
% S
% Thr:
0
0
8
0
8
72
0
0
0
8
0
0
0
0
0
% T
% Val:
15
0
0
0
8
0
0
0
0
8
0
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _